PICO Question Examples

20 PICO Question Examples
- In patients with type 2 diabetes, does treatment with metformin reduce the risk of cardiovascular disease compared to treatment with sulfonylurea drugs?
- In adults with hypertension, is blood pressure control achieved more effectively with angiotensin converting enzyme inhibitors or with calcium channel blockers?
- In postmenopausal women, does hormone replacement therapy increase the risk of breast cancer compared to placebo?
- In patients with acute respiratory distress syndrome, does the use of mechanical ventilation with lower tidal volumes reduce mortality compared to traditional tidal volumes?
- In patients with major depressive disorder, does cognitive behavioral therapy lead to greater improvement in symptoms compared to antidepressant medication?
- In children with attention-deficit/hyperactivity disorder, does stimulant medication improve academic and behavioral outcomes compared to behavioral therapy alone?
- In patients with severe acne, does isotretinoin treatment result in longer lasting remission compared to oral antibiotics?
- In patients with chronic low back pain, does acupuncture provide greater pain relief than sham acupuncture?
- In patients with chronic obstructive pulmonary disease, does pulmonary rehabilitation improve exercise capacity and quality of life compared to standard medical care alone?
- In patients with osteoarthritis of the knee, does total knee replacement result in greater improvement in pain and function compared to non-surgical management?
- In patients with stroke, does the use of intravenous thrombolysis within 3 hours of symptom onset improve functional outcome compared to placebo?
- In patients with HIV, does antiretroviral therapy reduce the risk of transmission to sexual partners compared to no treatment?
- In patients with type 1 diabetes, does continuous glucose monitoring improve glycemic control compared to self-monitoring of blood glucose?
- In patients with acute myocardial infarction, does primary percutaneous coronary intervention result in improved survival compared to fibrinolytic therapy?
- In patients with advanced cancer, does palliative care improve quality of life and decrease symptom burden compared to standard cancer treatment alone?
- In patients with chronic obstructive pulmonary disease, does long-term oxygen therapy improve survival compared to no oxygen therapy?
- In patients with schizophrenia, does the use of atypical antipsychotic medications result in greater improvement in symptoms compared to typical antipsychotic medications?
- In patients with alcohol use disorder, does psychosocial intervention reduce the risk of relapse compared to pharmacotherapy alone?
- In patients with chronic kidney disease, does early referral to a nephrologist improve outcomes compared to delayed referral?
- In patients with type 2 diabetes, does a low carbohydrate diet result in greater weight loss and improvement in glycemic control compared to a low fat diet?
Community Health and Population-Focused Nursing Field Experience
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